A recent study published in Food & Function (DOI: 10.1039/d4fo04446k) by Huang Huaxue, Chairman of Huacheng Biotech, in collaboration with Xiao Wenjun’s team from the National Engineering Technology Research Center for Plant Functional Ingredients, sheds new light on the health benefits of natural sugar substitutes.

 

The research explored the comparative effects of several sugar alternatives—mogroside V (MOG V), stevioside (ST), sucralose (TGS), and erythritol (ERT)—on intestinal health in type 2 diabetic (T2DM) mice.

Key Findings:
· Mogroside V significantly improved intestinal barrier function.
· It effectively reduced inflammatory responses, a key factor in chronic metabolic conditions.
· MOG V helped regulate gut microbiota composition, an essential element in metabolic and immune health.

Among all tested sweeteners, Mogroside V demonstrated the most comprehensive positive effects on gut health, highlighting its potential as a functional ingredient in the dietary management of T2DM.
As the global demand for clean-label, natural, and functional food ingredients continues to rise, Mogroside V—a key active compound in monk fruit extract—stands out as a promising solution for health-conscious consumers and patients managing diabetes.

This groundbreaking study reinforces Huacheng Biotech’s commitment to advancing the science of monk fruit and driving innovation in natural sweetening solutions.